Down-regulation of alpha-2u globulin in renal mitochondria of STZ-induced diabetic rats observed by a proteomic method
SH Sun, SQ Liu, CP Cai, R Cai, L Chen… - Annales d' …, 2012 - Elsevier
Aim.–To identify the changes of mitochondrial protein expression in diabetic renal
parenchyma and to characterize their molecular functions and biological processes in
diabetes. Methods.–Mitochondrial proteins extracted from renal parenchyma mitochondria of
streptozotocin-induced diabetic rats and normal rats were separated by two-dimensional
polyacrylamide gel electrophoresis and identified by matrix-assisted laser
desorption/ionization tandem time-of-flight mass spectrometry. Results.–Eleven proteins …
parenchyma and to characterize their molecular functions and biological processes in
diabetes. Methods.–Mitochondrial proteins extracted from renal parenchyma mitochondria of
streptozotocin-induced diabetic rats and normal rats were separated by two-dimensional
polyacrylamide gel electrophoresis and identified by matrix-assisted laser
desorption/ionization tandem time-of-flight mass spectrometry. Results.–Eleven proteins …
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